D-Dimer Quantitative Test Reagent
D-Dimer is a specific degradation product of cross-linked fibrin under the action of plasmin.The content of D-Dimer in normal body plasma is very low. Its increase indicates that fibrinthrombosis and fibrinolysis have occurred in the body.As one of the molecular markers ofhypercoagulability and hyperfibrinolysis in vivo. D-dimer is a sensitive indicator of DIC (disseminated intravascular coagulation) and a marker of systemic thrombosis (such aspulmonary embolism), and its elevation has diagnostic significance for DIC and systemic thrombosis. In addition D-dimer is also a marker of hypercoagulable states such as tumors and heart disease.
Features：
● Animal: Canine, Feline
● Sample type and volume: Whole blood 15μL Plasma 10μL
● Detection range： 50-10000 ng/mL
● Reaction time: 5 min
● 4-30°storage, 24 months shelf life
| TEST ITEM | SAMPLE TYPE/SAMPLE VOLUME | MIXTURE VOLUME | INCUBATION TIME | SIGNIFICANCES AND APPLICATIONS | RESULT INTERPRETATION | Specificity | Sensitivity | Detection range | Accuracy/Correlation | ||||
| D-dimer | Whole blood 15uL/ (EDTA K2-Plasma) 10uL |
75uL | 5min | D-dimer is a soluble degradation product of cross-linked fibrin under the action of fibrinolysis system and is a specific marker of fibrinolysis process.In clinical practice, blood is in a state of high coagulation. During the occurrence and development of disseminated intravascular coagulation and vascular diseases, D-dimer may be increased. Combined with clinical manifestations, D-dimer detection can be used to prevent thrombosis. |
0-250ng/mL Basically normal | 100.00% | 50 ng/mL | 50~10000 ng/mL | R2=0.95 | ||||
| 250-1000ng/mL Thrombosis cannot be ruled out | |||||||||||||
| ＞1000ng/mL Thrombus or DIC may be present and further examination is required | |||||||||||||
